Familial translocation t(1;9) associated with macromastia: molecular cloning of the breakpoints.
نویسندگان
چکیده
A familial reciprocal translocation associated with severe macromastia has been characterized by molecular cytogenetic and molecular analysis. Cloning of the translocation breakpoints revealed that no known gene has been disrupted by this translocation. Therefore, a position effect compromising the regulation of a still to be identified gene in the vicinity of the breakpoints can be assumed.
منابع مشابه
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عنوان ژورنال:
- Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation
دوره 1 1 شماره
صفحات -
تاریخ انتشار 2007